◎　Zhumadian Pharmaceutical Factory was founded in 1969.
◎　Annexed Zhumadian Phosphorous Fertilizer Factory in 1983.
◎　Annexed Zhumadian Monosodium Glutamate Factory in 1990.
◎　Top Ten Excellent Enterprise in Henan Pharmaceutical Industry awared by Henan Provincial Government in 1995
◎　Renamed into Henan Topfond Pharmaceutical Co., Ltd. in 1998
◎　New & high-tech enterprise certified by Ministry of Science and Technology and the Chinese Academy of Sciencers in 1999
◎　GMP certificate for injection and transfusion was received in 2000
◎　Public list company of Shanghai Stock Exchange since Dec.,2000
◎　Research center of Biotech was founded with East China University of Science and Technology at Shanghai in 2001
◎　Reorganizd and set up Henan Topfond Chinese Traditional Medicine Co., Ltd. in Jan. 2002.
◎　Shanghai Topfond Zhongke Pharmatech Co., Ltd., was founded with Shanghai Drug Research Institute of Chinese Academy of Sciencer in Apr., 2002
◎　Baotou Topfond Medicine Co., Ltd. was founded in Sep. 2002
◎　Heilingjiang Topfond Medicine Co., Ltd. was founded in Nov.,2002
◎　GMP certificate for Solid Finished Dosage Forms was received in Mar., 2003
◎　Top 100 Excellent Environmental Protection Projects awarded by National Environmental Protection Bureau in Jul., 2003
◎　Torch Prize awarded for Fleroxacin and its finished dosage forms by The Ministry of Science and Technology in Sep.,2003
◎　ISO9001 certificate was received in Dec., 2003
◎　GMP Certificate for APIs(Spiramycin, Acetylspiramycin,etc,) was received in May,2004
◎　ISO14001 Certification was recognized in May,2004 and certificate will be received later.